| Labetalol price in South Africa | 2 | R738 | — | Compare |
| Lacosamide price in South Africa | 4 | R339 | R5.65 | Compare |
| Lamivudine price in South Africa | 26 | R47.29 | R0.79 | Compare |
| Lamivudine and Nevirapine price in South Africa | 1 | R337 | R5.61 | — |
| Lamivudine and Nevirapine and Stavudine price in South Africa | 5 | R352 | R6.87 | — |
| Lamivudine and Nevirapine and Zidovudine price in South Africa | 2 | R764 | R12.74 | — |
| Lamivudine and Tenofovir price in South Africa | 2 | R208 | R7.34 | — |
| Lamivudine and Zidovudine price in South Africa | 7 | R195 | R3.25 | — |
| Lamotrigine price in South Africa | 69 | R88.72 | R3.16 | Compare |
| Lanreotide price in South Africa | 3 | R19,848 | — | — |
| Lansoprazole price in South Africa | 37 | R37.32 | R4.15 | Compare |
| Lapatinib price in South Africa | 2 | R16,151 | R231 | Compare |
| Laronidase price in South Africa | 1 | R11,715 | — | — |
| Latanoprost price in South Africa | 6 | R121 | — | — |
| Latanoprost and Timilol price in South Africa | 1 | R223 | — | — |
| Latanoprost and Timolol price in South Africa | 3 | R177 | — | — |
| Latanoprostene Bunod price in South Africa | 1 | R448 | — | — |
| Ledipasvir and Sofosbuvir price in South Africa | 1 | R9,155 | R327 | — |
| Leflunomide price in South Africa | 12 | R720 | R24.01 | Compare |
| Lemborexant price in South Africa | 2 | R411 | R19.34 | Compare |
| Lenalidomide price in South Africa | 22 | R2,583 | R193 | Compare |
| Lenvatinib price in South Africa | 2 | R13,686 | R1,140 | Compare |
| Lercanidipine price in South Africa | 16 | R177 | R5.90 | Compare |
| Letermovir price in South Africa | 2 | R4,081 | R2,604 | Compare |
| Letrozole price in South Africa | 9 | R409 | R13.65 | Compare |
| Leucovorin price in South Africa | 6 | R50.73 | R33.76 | Compare |
| Leuprolide price in South Africa | 9 | R2,186 | — | — |
| Leuprorelin price in South Africa | 1 | R2,551 | — | — |
| Levetiracetam price in South Africa | 25 | R65.59 | R2.04 | Compare |
| Levetiracetam and Salmeterol price in South Africa | 1 | R612 | — | — |
| Levobupivacaine price in South Africa | 4 | R433 | — | — |
| Levobupivicane price in South Africa | 1 | R373 | — | — |
| Levocabastine price in South Africa | 2 | R145 | — | — |
| Levocetirizine price in South Africa | 36 | R29.87 | R2.99 | Compare |
| Levocetirizine and Montelukast price in South Africa | 2 | R165 | R10.99 | — |
| Levocetirizine Dihydrochliride and Montelukast price in South Africa | 1 | R276 | R9.21 | — |
| Levofloxacin price in South Africa | 58 | R48.02 | R20.44 | Compare |
| Levofloxicin price in South Africa | 1 | R146 | R29.20 | — |
| Levonordefrin and Mepivacaine price in South Africa | 1 | R1,097 | — | — |
| Levonorgestrel price in South Africa | 17 | R58.67 | R58.67 | Compare |
| Levothyroxine price in South Africa | 29 | R12.34 | R0.86 | Compare |
| Levothyroxine and Liothyronine price in South Africa | 1 | R170 | R1.70 | — |
| Lidocaine price in South Africa | 17 | R60.94 | — | — |
| Lidocaine and Noradrenaline price in South Africa | 1 | R974 | — | — |
| Lidocaine and Prilocaine price in South Africa | 4 | R98.13 | — | — |
| Lincomycin price in South Africa | 2 | R42.18 | — | — |
| Lincomycin and Tamoxifen price in South Africa | 1 | R161 | R5.36 | — |
| Lindane price in South Africa | 1 | R59.54 | — | — |
| Linezolid price in South Africa | 24 | R235 | R73.07 | Compare |
| Liothyronine price in South Africa | 2 | R164 | R3.29 | Compare |
| Lipegfilgrastim price in South Africa | 1 | R3,533 | — | — |
| Liraglutide price in South Africa | 6 | R1,019 | — | — |
| Lisdexamfetamine Dimesilate price in South Africa | 12 | R720 | R24.01 | — |
| Lisinopril price in South Africa | 26 | R28.47 | R0.95 | Compare |
| Lithium price in South Africa | 3 | R534 | R5.34 | — |
| Lithium Carbonate price in South Africa | 1 | R397 | R6.62 | Compare |
| Live Attenuated and Measles price in South Africa | 1 | R201 | — | — |
| Live Attenuated and Varicella price in South Africa | 1 | R539 | — | — |
| Live Attenuated Cam and Measles price in South Africa | 1 | R1,979 | — | — |
| Lodoxamide price in South Africa | 2 | R120 | — | — |
| Lofepramine price in South Africa | 2 | R387 | R12.89 | Compare |
| Lomefloxacin price in South Africa | 3 | R160 | R53.31 | Compare |
| Loperamide price in South Africa | 17 | R10.64 | R0.75 | Compare |
| Loperamide and Simethicone price in South Africa | 1 | R57.81 | R9.63 | — |
| Loperamidehydrochloride price in South Africa | 1 | R34.70 | R3.47 | — |
| Lopinavir and Ritonavir price in South Africa | 7 | R112 | R3.18 | — |
| Loprazolam price in South Africa | 2 | R471 | R15.70 | — |
| Loracarbef price in South Africa | 3 | R231 | R35.88 | — |
| Loratadine price in South Africa | 38 | R13.10 | R1.59 | Compare |
| Loratadine and Pseudoephedrine price in South Africa | 2 | R52.46 | R8.74 | — |
| Lorazepam price in South Africa | 8 | R151 | R2.06 | Compare |
| Lormetazepam price in South Africa | 4 | R289 | R9.64 | Compare |
| Lornoxicam price in South Africa | 12 | R52.42 | R7.02 | Compare |
| Losartan price in South Africa | 38 | R68.52 | R2.28 | Compare |
| Loteprednol Etabonate price in South Africa | 3 | R197 | — | — |
| Loteprendol Etabonate and Tobramycin price in South Africa | 1 | R272 | — | — |
| Lovastatin price in South Africa | 2 | R214 | R7.12 | Compare |
| Loxaglic Acid price in South Africa | 5 | R325 | — | — |
| Lurasidone price in South Africa | 5 | R773 | R27.80 | Compare |
| Lutropin Alfa price in South Africa | 1 | R378 | — | — |
| Lymecycline price in South Africa | 4 | R239 | R12.40 | Compare |