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Medicine prices in South Africa

Letrozole Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R13.65

Cheapest 2.5 mg tablet: Letrozole 2.5mg Hetero, R409 for 30 tablets. Official SEP list, Oct 2026.

≈ $0.82 per tablet
R409
cheapest pack (30 tablets)
R409
30 tablets (1 a day for a month)
9
listed products
SEP
price type
What you actually pay

What a patient pays for letrozole in South Africa

R409
official SEP for Letrozole 2.5mg Hetero, 30 tablets
+ R205
maximum dispensing fee incl. VAT
Up to R614
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

9 products

9 different brand names across 1 strength are on the official list.

3.6× for the original

The originator brand Femara 2,5 costs R48.92 per tablet; the cheapest generic, Letrozole 2.5mg Hetero, costs R13.65.

India

has the lowest listed price per tablet for the same strength: $0.034 vs $0.82 here (different price types; see below).

Interactive

How much will Letrozole 2.5 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R13.65 per tablet.

Estimated cost
R409
For a full yearR4,982
Per tablet in USD$0.822
Every listed product

All 9 letrozole products in South Africa

Letrozole official prices in South Africa
ProductStrength and formPackPricePer unit
Letrozole 2.5mg Hetero2.5 mg film-coated tablet30 tabletsR409R13.65
Cipla Letrozole 2,52.5 mg film-coated tablet30 tabletsR461R15.38
ROZILAT2.5 mg film-coated tablet30 tabletsR475R15.83
Letraz2.5 mg tablet30 tabletsR475R15.83
Trozolt2.5 mg tablet30 tabletsR1,242R41.41
Femara 2,5 original2.5 mg tablet30 tabletsR1,468R48.92
Laradexfilm-coated tablet30 tabletsR409R13.63
Femzole 2.5tablet30 tabletsR430R14.34
Accord Letrozole 2,5 mgfilm-coated tablet30 tabletsR461R15.38
Letrozole 2.5mg HeteroR13.65
Cipla Letrozole 2,5R15.38
ROZILATR15.83
LetrazR15.83
TrozoltR41.41
Femara 2,5R48.92
Letrozole 2.5 mg tablet: price per tablet by product (ZAR)
Same medicine, other countries

Letrozole 2.5 mg tablet: South Africa vs 5 other countries

India$0.034
United Kingdom$0.10
United States$0.15
Australia$0.18
United Arab Emirates$0.25
South Africa (this page)$0.82
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹3.19$0.034
United KingdomNHS Drug Tariff price£0.076$0.10
United StatesNADAC pharmacy acquisition cost$0.15$0.15
AustraliaPBS approved ex-manufacturer priceA$0.25$0.18
United Arab EmiratesAbu Dhabi DoH public priceAED 0.93$0.25

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Strengths and forms

Every strength and form of letrozole in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
2.5 mg tablet6R409R13.65
tablet3R409R13.63

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of letrozole in South Africa

6 brand names of letrozole are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Letrozole manufacturers in South Africa

The official list names 9 manufacturers for letrozole in South Africa: Hetero Drugs South Africa (Pty) Ltd, Cipla Medpro (Pty) Ltd, Aurogen South Africa (Pty) Ltd, Equity Pharmaceuticals (Pty) Ltd, Brimpharm Sa (Pty) Ltd, Novartis South Africa (Pty) Ltd, Eurolab (Pty) Ltd and Adcock Ingram Limited and 1 more.

A–Z

Other medicine prices in South Africa

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Quick answers

Frequently asked questions

How much does letrozole cost in South Africa?
Official SEPs for letrozole in South Africa range from R409 to R1,468 per pack across 9 listed products. The cheapest 2.5 mg tablet works out at R13.65 each (about $0.82).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for letrozole at a pharmacy in South Africa?
Up to R614 for Letrozole 2.5mg Hetero (30 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest letrozole 2.5 mg tablet in South Africa?
Letrozole 2.5mg Hetero at R409 for 30 tablets, or R13.65 per tablet. 5 other products have the same strength.
What brands of letrozole are sold in South Africa?
6 brand names are on the official list, including Laradex (from R409), Femzole (from R430), Rozilat (from R475), Letraz (from R475) and Trozolt (from R1,242).
Who makes letrozole sold in South Africa?
Manufacturers named on the official list include Hetero Drugs South Africa (Pty) Ltd, Cipla Medpro (Pty) Ltd, Aurogen South Africa (Pty) Ltd and Equity Pharmaceuticals (Pty) Ltd.
Is letrozole cheaper in other countries?
For 2.5 mg tablet, the lowest listed price per tablet is $0.034 in India, $0.10 in the United Kingdom, $0.15 in the United States and $0.18 in Australia, compared with $0.82 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error