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Medicine prices in the United States

Letrozole Price in the United States (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 31 October 2026How we get our data
Lowest NADAC pharmacy acquisition cost per tablet
$0.15

Average pharmacy cost for generic letrozole 2.5 mg tablet, across 14 product codes (NDCs). CMS NADAC file, Oct 2026.

≈ $0.15 per tablet
$4.51
30 tablets (pharmacy cost)
$13.52
90 tablets (pharmacy cost)
1
strength and form
NADAC
price type (CMS)
Cash price

Letrozole cost without insurance

The figures here are what US retail pharmacies pay for generic letrozole: about $0.15 per tablet (2.5 mg tablet), so $4.51 for a 30-day supply at one a day. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.

With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.

India

has the lowest listed price per tablet for the same strength: $0.034 vs $0.15 here (different price types; see below).

Interactive

How much will Letrozole 2.5 mg tablet cost you?

tablets per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many tablets you need. This is a cost estimate only, using $0.150 per tablet.

Estimated cost
$4.51
For a full year$54.82
Every listed product

All 1 letrozole product in the United States

Letrozole official prices in the United States
Generic (NADAC description)StrengthFormPer unit30 units
letrozole 2.5 mg tablet2.5 mgtablet$0.15$4.51
Same medicine, other countries

Letrozole 2.5 mg tablet: the United States vs 5 other countries

India$0.034
United Kingdom$0.10
United States (this page)$0.15
Australia$0.18
United Arab Emirates$0.25
South Africa$0.82
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹3.19$0.034
United KingdomNHS Drug Tariff price£0.076$0.10
AustraliaPBS approved ex-manufacturer priceA$0.25$0.18
United Arab EmiratesAbu Dhabi DoH public priceAED 0.93$0.25
South AfricaSingle Exit Price (SEP)R13.65$0.82

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How NADAC prices work in the United States

Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.

Read the full guide to medicine prices in the United States.

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Quick answers

Frequently asked questions

How much does letrozole cost in the United States?
Official NADAC prices for letrozole in the United States range from $0.15 to $0.15 per pack across 1 listed product. The cheapest 2.5 mg tablet works out at $0.15 each (about $0.15).
What kind of price is this?
It is the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
What is the cheapest letrozole 2.5 mg tablet in the United States?
Generic at $0.15 for 1 tablet, or $0.15 per tablet.
How much does letrozole cost without insurance?
US pharmacies pay about $0.15 per tablet for 2.5 mg tablet, or $4.51 for 30 (NADAC, Oct 2026). Without insurance you pay that cost plus the pharmacy's dispensing fee and margin, so cash prices are higher and vary a lot between pharmacies. Asking for the generic, comparing pharmacies and using a discount program usually brings the price closest to this cost.
Is NADAC the retail price of letrozole?
No. NADAC is what pharmacies pay to buy the drug. It is the closest public benchmark for the real cost of a generic, which is why Medicaid uses it to pay pharmacies, but the price at the counter includes fees on top.
Is letrozole cheaper in other countries?
For 2.5 mg tablet, the lowest listed price per tablet is $0.034 in India, $0.10 in the United Kingdom, $0.18 in Australia and $0.25 in the UAE, compared with $0.15 in the United States. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error