Esketamine Price in South Africa (2026)
Cheapest pack: SPRAVATO®, 28 mg nasal spray, 1. Official SEP list, Oct 2026.
≈ $332What a patient pays for esketamine in South Africa
Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
All 1 esketamine product in South Africa
| Product | Strength and form | Pack | Price | Per unit |
|---|---|---|---|---|
| SPRAVATO® original | 28 mg nasal spray | 1 | R5,509 | — |
How SEPs work in South Africa
Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
Brands of esketamine in South Africa
1 brand name of esketamine is on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.
Esketamine manufacturers in South Africa
The official list names 1 manufacturer for esketamine in South Africa: Janssen Pharmaceutica (Pty) Ltd.
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- Esmolol price1 productfrom R1,564
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Frequently asked questions
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Sources
- National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
- National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
- European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.
Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error