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Brand prices in South Africa

Spravato Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R5,509

Spravato (esketamine): 28 mg nasal spray, 1. Official SEP list, Oct 2026.

≈ $332
R5,509
per pack
1
strength
1
listed pack
SEP
price type
3 countries

list Spravato: South Africa, Saudi Arabia and United Arab Emirates.

Every listed pack

Spravato strengths, packs and prices in South Africa

Spravato official prices in South Africa
ProductStrength and formPackPricePer unit
SPRAVATO® original28 mg nasal spray1R5,509—

Spravato is sold in South Africa as 28 mg nasal spray. The official list names Janssen Pharmaceutica (Pty) Ltd as the manufacturer. It is a Schedule 5 medicine. The South African price database marks it as the originator (first) brand.

Same brand, other countries

Spravato price in other countries

By country
CountryPacksCheapest pack (local)In USDPrice type
South Africa (this page)1R5,509$332Single Exit Price (SEP)
Saudi Arabia3SAR 953$254SFDA public price
United Arab Emirates3AED 1,239$337Abu Dhabi DoH public price

Pack sizes differ between countries, and each country publishes a different kind of price.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every esketamine product and price in South Africa, or read the guide to medicine prices in South Africa.

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Quick answers

Frequently asked questions

How much does Spravato cost in South Africa?
Spravato costs R5,509. This is the Single Exit Price.
What is the generic name of Spravato?
Spravato contains esketamine. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.
Who makes Spravato?
The official list names Janssen Pharmaceutica (Pty) Ltd as the manufacturer of Spravato products sold in South Africa.
What schedule is Spravato in South Africa?
Spravato is a Schedule 5 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error