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Medicine prices in the United States

Sertraline Price in the United States (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 31 October 2026How we get our data
Lowest NADAC pharmacy acquisition cost per tablet
$0.051

Average pharmacy cost for generic sertraline 100 mg tablet, across 41 product codes (NDCs). CMS NADAC file, Oct 2026.

≈ $0.051 per tablet
$1.53
30 tablets (pharmacy cost)
$4.60
90 tablets (pharmacy cost)
6
strengths and forms
NADAC
price type (CMS)
Cash price

Sertraline cost without insurance

The figures here are what US retail pharmacies pay for generic sertraline: about $0.051 per tablet (100 mg tablet), so $1.53 for a 30-day supply at one a day. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.

With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.

6 products

One product name across 6 strengths are on the official list.

India

has the lowest listed price per tablet for the same strength: $0.022 vs $0.051 here (different price types; see below).

Interactive

How much will Sertraline 100 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using $0.051 per tablet.

Estimated cost
$1.53
For a full year$18.65
Every listed product

All 6 sertraline products in the United States

Sertraline official prices in the United States
Generic (NADAC description)StrengthFormPer unit30 units
sertraline hcl 100 mg tablet100 mgtablet$0.051$1.53
sertraline 150 mg capsule150 mgcapsule$1.15$34.38
sertraline 200 mg capsule200 mgcapsule$1.47$44.10
sertraline 20 mg/mL oral conc20 mgother$0.39$11.80
sertraline hcl 25 mg tablet25 mgtablet$0.028$0.85
sertraline hcl 50 mg tablet50 mgtablet$0.035$1.04
Same medicine, other countries

Sertraline 100 mg tablet: the United States vs 5 other countries

India$0.022
United States (this page)$0.051
United Kingdom$0.053
Australia$0.058
South Africa$0.17
United Arab Emirates$0.62
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹2.06$0.022
United KingdomNHS Drug Tariff price£0.040$0.053
AustraliaPBS approved ex-manufacturer priceA$0.083$0.058
South AfricaSingle Exit Price (SEP)R2.87$0.17
United Arab EmiratesAbu Dhabi DoH public priceAED 2.27$0.62

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How NADAC prices work in the United States

Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.

Read the full guide to medicine prices in the United States.

Strengths and forms

Every strength and form of sertraline in the United States

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
100 mg tablet1$0.051$0.051
150 mg capsule1$1.15$1.15
200 mg capsule1$1.47$1.47
20 mg other1$0.39—
25 mg tablet1$0.028$0.028
50 mg tablet1$0.035$0.035

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

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Quick answers

Frequently asked questions

How much does sertraline cost in the United States?
Official NADAC prices for sertraline in the United States range from $0.051 to $1.47 per pack across 6 listed products. The cheapest 100 mg tablet works out at $0.051 each (about $0.051).
What kind of price is this?
It is the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
What is the cheapest sertraline 100 mg tablet in the United States?
Generic at $0.051 for 1 tablet, or $0.051 per tablet.
How much does sertraline cost without insurance?
US pharmacies pay about $0.051 per tablet for 100 mg tablet, or $1.53 for 30 (NADAC, Oct 2026). Without insurance you pay that cost plus the pharmacy's dispensing fee and margin, so cash prices are higher and vary a lot between pharmacies. Asking for the generic, comparing pharmacies and using a discount program usually brings the price closest to this cost.
Is NADAC the retail price of sertraline?
No. NADAC is what pharmacies pay to buy the drug. It is the closest public benchmark for the real cost of a generic, which is why Medicaid uses it to pay pharmacies, but the price at the counter includes fees on top.
Is sertraline cheaper in other countries?
For 100 mg tablet, the lowest listed price per tablet is $0.022 in India, $0.053 in the United Kingdom, $0.058 in Australia and $0.17 in South Africa, compared with $0.051 in the United States. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error