Methotrexate Solution Price in South Africa (2026)
Cheapest pack: Emthexate Rtu 1000, 1000 mg/40ml injection, 40. Official SEP list, Oct 2026.
≈ $43.45What a patient pays for methotrexate solution in South Africa
Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
6 different brand names across 3 strengths are on the official list.
All 6 methotrexate solution products in South Africa
| Product | Strength and form | Pack | Price | Per unit |
|---|---|---|---|---|
| Emthexate Rtu 1000 | 1000 mg/40ml injection | 40 | R721 | — |
| Abitrexate 1 g | 1000 mg/10ml injection | 10 | R814 | — |
| Emthexate Rtu 50 | 50 mg/2ml injection | 2 | R33.80 | — |
| Abitrexate 50 | 50 mg injection | 1 | R56.54 | — |
| Abitrexate 500 | 500 mg/ml injection | 20 | R209 | — |
| Emthexate Rtu 500 | 500 mg/20ml injection | 20 | R339 | — |
How SEPs work in South Africa
Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
Every strength and form of methotrexate solution in South Africa
| Strength and form | Products | Cheapest pack | Cheapest per unit |
|---|---|---|---|
| 1000 mg injection | 2 | R721 | — |
| 50 mg injection | 2 | R33.80 | — |
| 500 mg injection | 2 | R209 | — |
Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.
Brands of methotrexate solution in South Africa
2 brand names of methotrexate solution are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.
Methotrexate Solution manufacturers in South Africa
The official list names 2 manufacturers for methotrexate solution in South Africa: Pharmachemie (Pty) Ltd and Teva Pharmaceuticals (Pty) Ltd.
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- Methotrexate price5 productsfrom R38.64
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Frequently asked questions
How much does methotrexate solution cost in South Africa?
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Sources
- National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
- National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
- European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.
Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error