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Medicine prices in the United States

Metformin and Sitagliptin Price in the United States (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 31 October 2026How we get our data
Lowest NADAC pharmacy acquisition cost per tablet
$2.51

Average pharmacy cost for generic metformin and sitagliptin 50 MG / 1,000 MG tablet, across 4 product codes (NDCs). CMS NADAC file, Oct 2026.

≈ $2.51 per tablet
$75.27
30 tablets (pharmacy cost)
$226
90 tablets (pharmacy cost)
5
strengths and forms
NADAC
price type (CMS)
Cash price

Metformin and Sitagliptin cost without insurance

The figures here are what US retail pharmacies pay for generic metformin and sitagliptin: about $2.51 per tablet (50 MG / 1,000 MG tablet), so $75.27 for a 30-day supply at one a day. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.

With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.

5 products

One product name across 3 strengths are on the official list.

India

has the lowest listed price per tablet for the same strength: $0.054 vs $2.51 here (different price types; see below).

Interactive

How much will Metformin and Sitagliptin 50 MG / 1,000 MG tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using $2.51 per tablet.

Estimated cost
$75.27
For a full year$916
Every listed product

All 5 metformin and sitagliptin products in the United States

Metformin and Sitagliptin official prices in the United States
Generic (NADAC description)StrengthFormPer unit30 units
sitagliptin phosphate-metformin 50 mg-1,000 mg tablet50 MG / 1,000 MGtablet$2.51$75.27
sitagliptin phosphate-metformin er 50 mg-500 mg tablet50 MG / 500 MGmodified-release tablet$3.74$112
sitagliptin phosphate-metformin er 50 mg-1,000 mg tablet50 MG / 1,000 MGmodified-release tablet$4.18$125
sitagliptin phosphate-metformin er 100 mg-1,000 mg tablet100 MG / 1,000 MGmodified-release tablet$8.34$250
sitagliptin phosphate-metformin 50 mg-500 mg tablet50 MG / 500 MGtablet$2.52$75.45
Same medicine, other countries

Metformin and Sitagliptin 50 MG / 1,000 MG tablet: the United States vs India

India$0.054
United States (this page)$2.51
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹5.16$0.054

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at ECB reference rates of 23 October 2026.

What this price means

How NADAC prices work in the United States

Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.

Read the full guide to medicine prices in the United States.

Its ingredients on their own
Strengths and forms

Every strength and form of metformin and sitagliptin in the United States

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
50 MG / 1,000 MG tablet1$2.51$2.51
50 MG / 500 MG modified-release tablet1$3.74$3.74
50 MG / 1,000 MG modified-release tablet1$4.18$4.18
100 MG / 1,000 MG modified-release tablet1$8.34$8.34
50 MG / 500 MG tablet1$2.52$2.52

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

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Quick answers

Frequently asked questions

How much does metformin and sitagliptin cost in the United States?
Official NADAC prices for metformin and sitagliptin in the United States range from $2.51 to $8.34 per pack across 5 listed products. The cheapest 50 MG / 1,000 MG tablet works out at $2.51 each (about $2.51).
What kind of price is this?
It is the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
What is the cheapest metformin and sitagliptin 50 MG / 1,000 MG tablet in the United States?
Generic at $2.51 for 1 tablet, or $2.51 per tablet.
How much does metformin and sitagliptin cost without insurance?
US pharmacies pay about $2.51 per tablet for 50 MG / 1,000 MG tablet, or $75.27 for 30 (NADAC, Oct 2026). Without insurance you pay that cost plus the pharmacy's dispensing fee and margin, so cash prices are higher and vary a lot between pharmacies. Asking for the generic, comparing pharmacies and using a discount program usually brings the price closest to this cost.
Is NADAC the retail price of metformin and sitagliptin?
No. NADAC is what pharmacies pay to buy the drug. It is the closest public benchmark for the real cost of a generic, which is why Medicaid uses it to pay pharmacies, but the price at the counter includes fees on top.
Is metformin and sitagliptin cheaper in other countries?
For 50 MG / 1,000 MG tablet, the lowest listed price per tablet is $0.054 in India, compared with $2.51 in the United States. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error