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Medicine prices in South Africa

Crizanlizumab Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R6,500

Cheapest pack: Ryverna 10mg/ml, 100 mg/10ml injection, 1. Official SEP list, Oct 2026.

≈ $392
R6,500
per pack
1
strength
1
listed product
SEP
price type
What you actually pay

What a patient pays for crizanlizumab in South Africa

R6,500
official SEP for Ryverna 10mg/ml, 1
+ R685
maximum dispensing fee incl. VAT
Up to R7,185
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

Every listed product

All 1 crizanlizumab product in South Africa

Crizanlizumab official prices in South Africa
ProductStrength and formPackPricePer unit
Ryverna 10mg/ml original100 mg/10ml injection1R6,500—
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Brand names

Brands of crizanlizumab in South Africa

1 brand name of crizanlizumab is on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Crizanlizumab manufacturers in South Africa

The official list names 1 manufacturer for crizanlizumab in South Africa: Novartis South Africa (Pty) Ltd.

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Quick answers

Frequently asked questions

How much does crizanlizumab cost in South Africa?
Official SEPs for crizanlizumab in South Africa range from R6,500 to R6,500 per pack across 1 listed product.
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for crizanlizumab at a pharmacy in South Africa?
Up to R7,185 for Ryverna 10mg/ml (1). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What brands of crizanlizumab are sold in South Africa?
1 brand name is on the official list, including Ryverna (from R6,500).
Who makes crizanlizumab sold in South Africa?
Manufacturers named on the official list include Novartis South Africa (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error