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Ryverna Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R6,500

Ryverna (crizanlizumab): 100 mg/10ml injection, 1. Official SEP list, Oct 2026.

≈ $392
R6,500
per pack
1
strength
1
listed pack
SEP
price type
Every listed pack

Ryverna strengths, packs and prices in South Africa

Ryverna official prices in South Africa
ProductStrength and formPackPricePer unit
Ryverna 10mg/ml original100 mg/10ml injection1R6,500—

Ryverna is sold in South Africa as 100 mg injection. The official list names Novartis South Africa (Pty) Ltd as the manufacturer. It is a Schedule 4 medicine. The South African price database marks it as the originator (first) brand.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every crizanlizumab product and price in South Africa, or read the guide to medicine prices in South Africa.

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Quick answers

Frequently asked questions

How much does Ryverna cost in South Africa?
Ryverna costs R6,500. This is the Single Exit Price.
What is the generic name of Ryverna?
Ryverna contains crizanlizumab. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.
Who makes Ryverna?
The official list names Novartis South Africa (Pty) Ltd as the manufacturer of Ryverna products sold in South Africa.
What schedule is Ryverna in South Africa?
Ryverna is a Schedule 4 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error