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Zosert Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R10.88

Zosert (sertraline): 50 mg tablet, R326 for 30 tablets. Official SEP list, Oct 2026.

≈ $0.66 per tablet
R326
per pack
R326
30 tablets at the lowest price
1
listed pack
−75%
cheapest same-strength alternative
75% less

TRALIDEP 50 costs R2.69 per tablet for sertraline 50 mg tablet, against R10.88 for Zosert.

11 brands

of sertraline are listed in South Africa, including Tralidep, Serlife and Zylin.

Every listed pack

Zosert strengths, packs and prices in South Africa

Zosert official prices in South Africa
ProductStrength and formPackPricePer unit
Zosert 5050 mg tablet30 tabletsR326R10.88

Zosert is sold in South Africa as 50 mg tablet. The official list names Ranbaxy Pharmaceuticals (Pty) Ltd as the manufacturer. It is a Schedule 5 medicine. The South African price database marks it as a generic.

Same ingredient, same strength

Zosert vs other sertraline 50 mg tablet in South Africa

TRALIDEP 50R2.69
Dyna Sertraline 50R3.10
Serlife 50R3.47
Serdep-50R3.98
Zylin 50R4.24
Arysert 50R4.27
Zolid 50 mgR4.76
Sertraline-Winthrop 50 mgR5.91
Arrow Sertraline 50R6.90
Sertra Tablets 50mgR7.36
sertraline 50 mg tablet: price per tablet (ZAR)
Alternatives
ProductPackPricePer unit
TRALIDEP 5030 tabletsR80.78R2.69
Dyna Sertraline 5030 tabletsR92.90R3.10
Serlife 5030 tabletsR104R3.47
Serdep-5030 tabletsR119R3.98
Zylin 5030 tabletsR127R4.24
Arysert 5030 tabletsR128R4.27
Zolid 50 mg30 tabletsR143R4.76
Sertraline-Winthrop 50 mg30 tabletsR177R5.91
Arrow Sertraline 5030 tabletsR207R6.90
Sertra Tablets 50mg30 tabletsR221R7.36

Products with the same active ingredient, strength and form are usually interchangeable, but check with your doctor or pharmacist before switching, especially for modified-release forms.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every sertraline product and price in South Africa, or read the guide to medicine prices in South Africa.

Other brands of sertraline

Sertraline brands in South Africa

Keep exploring

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Quick answers

Frequently asked questions

How much does Zosert cost in South Africa?
Zosert costs R326; the lowest price per tablet is R10.88 (about $0.66). This is the Single Exit Price.
What is the generic name of Zosert?
Zosert contains sertraline. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.
Is there a cheaper alternative to Zosert in South Africa?
Yes. For sertraline 50 mg tablet, TRALIDEP 50 is listed at R80.78 for 30 tablets, about 75% less than Zosert. Ask your doctor or pharmacist whether switching is right for you.
Who makes Zosert?
The official list names Ranbaxy Pharmaceuticals (Pty) Ltd as the manufacturer of Zosert products sold in South Africa.
What schedule is Zosert in South Africa?
Zosert is a Schedule 5 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error