Brand prices in South Africa

Nexmezol Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data

Lowest Single Exit Price (SEP) per tablet

R17.04

Nexmezol (esomeprazole): 40 mg tablet, R238 for 14 tablets. Official SEP list, Oct 2026.

≈ $1.03 per tablet

R238 – R477

per pack

R511

30 tablets at the lowest price

listed packs

−71%

cheapest same-strength alternative

71% less

Hetenex 40 Injection costs R4.97 per tablet for esomeprazole 40 mg tablet, against R17.04 for Nexmezol.

13 brands

of esomeprazole are listed in South Africa, including Hetenex, Nectizole Iv and Nextell Otc.

Every listed pack

Nexmezol strengths, packs and prices in South Africa

Nexmezol official prices in South Africa
Product	Strength and form	Pack	Price	Per unit
Nexmezol 40	40 mg tablet	14 tablets	R238	R17.04
Nexmezol 40	40 mg tablet	28 tablets	R477	R17.04

Nexmezol is sold in South Africa as 40 mg tablet. The official list names Sandoz SA (Pty) Ltd as the manufacturer. It is a Schedule 4 medicine. The South African price database marks it as a generic.

Same ingredient, same strength

Nexmezol vs other esomeprazole 40 mg tablet in South Africa

Hetenex 40 InjectionR4.97

Trusfluks 40R9.43

Truloc 40 mgR12.29

Truloc 40 mgR12.30

Jubigord 40R12.85

Fluxtrin 40R13.19

NEXILOK 40R13.51

Esomeprazole 40 UnicornR14.17

Nextell 40 mgR14.25

esomeprazole 40 mg tablet: price per tablet (ZAR)

Alternatives
Product	Pack	Price	Per unit
Hetenex 40 Injection	5 tablets	R24.85	R4.97
Hetenex 40 Injection	25 tablets	R124	R4.97
Trusfluks 40	28 tablets	R264	R9.43
Truloc 40 mg	14 tablets	R172	R12.29
Truloc 40 mg	30 tablets	R369	R12.30
Jubigord 40	30 tablets	R386	R12.85
Fluxtrin 40	30 tablets	R396	R13.19
NEXILOK 40	28 tablets	R378	R13.51
Esomeprazole 40 Unicorn	28 tablets	R397	R14.17
Nextell 40 mg	28 tablets	R399	R14.25

Products with the same active ingredient, strength and form are usually interchangeable, but check with your doctor or pharmacist before switching, especially for modified-release forms.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every esomeprazole product and price in South Africa, or read the guide to medicine prices in South Africa.

Other brands of esomeprazole

Esomeprazole brands in South Africa

Keep exploring

What people check next

All esomeprazole prices in South Africa
74 listed products→More brands in South Africa (N)
A–Z list of brand names→

Quick answers

Frequently asked questions

How much does Nexmezol cost in South Africa?

Nexmezol costs from R238 to R477 depending on strength and pack; the lowest price per tablet is R17.04 (about $1.03). This is the Single Exit Price.

What is the generic name of Nexmezol?

Nexmezol contains esomeprazole. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.

Is there a cheaper alternative to Nexmezol in South Africa?

Yes. For esomeprazole 40 mg tablet, Hetenex 40 Injection is listed at R24.85 for 5 tablets, about 71% less than Nexmezol. Ask your doctor or pharmacist whether switching is right for you.

Who makes Nexmezol?

The official list names Sandoz SA (Pty) Ltd as the manufacturer of Nexmezol products sold in South Africa.

What schedule is Nexmezol in South Africa?

Nexmezol is a Schedule 4 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.

Evidence

Sources

National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error