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Medicine prices in South Africa

Zoledronic Acid Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R421

Cheapest pack: ZOLEDRONIC ACID 4mg/5ml FRESENIUS, 4 mg/5ml injection, 5. Official SEP list, Oct 2026.

≈ $25.38
R421 – R2,697
per pack
2
strengths
11
listed products
SEP
price type
What you actually pay

What a patient pays for zoledronic acid in South Africa

R421
official SEP for ZOLEDRONIC ACID 4mg/5ml FRESENIUS, 5
+ R209
maximum dispensing fee incl. VAT
Up to R630
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

11 products

11 different brand names across 2 strengths are on the official list.

Every listed product

All 11 zoledronic acid products in South Africa

Zoledronic Acid official prices in South Africa
ProductStrength and formPackPricePer unit
ZOLEDRONIC ACID 4mg/5ml FRESENIUS4 mg/5ml injection5R421—
Eurodron4 mg/5 ml infusion5R493—
Zoltero4 mg/5ml infusion5R503—
Zoldron4 mg/5ml infusion5R943—
Zometa 4 mg original4 mg injection5R958—
Zosteopor4 mg/5ml infusion5R1,005—
Zomedron4 mg powder for injection10R1,048—
Zolapor4 mg/5ml infusion5R1,330—
Zoclasta 5mg/100ml5 mg/100ml infusion100R2,249—
Aclasta original5 mg/100ml injection100R2,697—
Zobone4 mg powder5R495—
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Strengths and forms

Every strength and form of zoledronic acid in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
4 mg injection8R421—
5 mg injection2R2,249—
4 mg powder1R495—

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of zoledronic acid in South Africa

10 brand names of zoledronic acid are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Zoledronic Acid manufacturers in South Africa

The official list names 11 manufacturers for zoledronic acid in South Africa: Fresenius Kabi South Africa (Pty) Ltd, Eurolab (Pty) Ltd, Hetero Drugs South Africa (Pty) Ltd, Accord Healthcare (Pty) Ltd, Novartis South Africa (Pty) Ltd, Adcock Ingram Critical Care (Pty) Ltd, Cipla Medpro (Pty) Ltd and Activo Health (Pty) Ltd and 3 more.

A–Z

Other medicine prices in South Africa

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Quick answers

Frequently asked questions

How much does zoledronic acid cost in South Africa?
Official SEPs for zoledronic acid in South Africa range from R421 to R2,697 per pack across 11 listed products.
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for zoledronic acid at a pharmacy in South Africa?
Up to R630 for ZOLEDRONIC ACID 4mg/5ml FRESENIUS (5). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What brands of zoledronic acid are sold in South Africa?
10 brand names are on the official list, including Eurodron (from R493), Zobone (from R495), Zoltero (from R503), Zoldron (from R943) and Zometa (from R958).
Who makes zoledronic acid sold in South Africa?
Manufacturers named on the official list include Fresenius Kabi South Africa (Pty) Ltd, Eurolab (Pty) Ltd, Hetero Drugs South Africa (Pty) Ltd and Accord Healthcare (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error