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Medicine prices in South Africa

Valproate Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R4.46

Cheapest 100 mg tablet: Epilim 100 Crushable, R446 for 100 tablets. Official SEP list, Oct 2026.

≈ $0.27 per tablet
R446
cheapest pack (100 tablets)
R134
30 tablets (1 a day for a month)
36
listed products
SEP
price type
What you actually pay

What a patient pays for valproate in South Africa

R446
official SEP for Epilim 100 Crushable, 100 tablets
+ R206
maximum dispensing fee incl. VAT
Up to R652
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

36 products

36 different brand names across 12 strengths are on the official list.

Australia

has the lowest listed price per tablet for the same strength: $0.073 vs $0.27 here (different price types; see below).

Interactive

How much will Valproate 100 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R4.46 per tablet.

Estimated cost
R134
For a full yearR1,626
Per tablet in USD$0.268
Every listed product

All 36 valproate products in South Africa

Valproate official prices in South Africa
ProductStrength and formPackPricePer unit
Epilim 100 Crushable original100 mg tablet100 tabletsR446R4.46
Convulex 150 original150 mg capsule100 capsulesR375R3.75
Convulex 300 original300 mg capsule100 capsulesR750R7.50
Convulex 500 original500 mg capsule100 capsulesR1,231R12.31
Cerepiv IV400 mg/4ml injection4R76.90—
Epilizine Intravenous 400400 mg/4ml injection4R112—
Navalpro 400mg/4ml400 mg/4ml injection4R133—
EVALEX 400 mg IV400 mg infusion4R427—
NAVALZYD 400 mg IV400 mg infusion20R467—
VELPALEX 400 mg IV400 mg infusion5R494—
Navilize 100mg/ml (4ml)400 mg/4ml injection20R562—
Epilim Intravenous original400 mg/4ml injection4R619—
Eprolep CR 200133.199 mg / 58 mg tablet100R331R3.31
Navalpro CR 200133.2 mg / 58 mg tablet100R336R3.36
Eprolep CR 300199.8 mg / 87 mg tablet100R496R4.96
Navalpro CR 300199.8 mg / 87 mg tablet100R503R5.03
Rubilim CR 200200 mg tablet60R199R3.31
Epilizine CR 200200 mg tablet100R446R4.46
Epilim CR 200 original200 mg tablet100R620R6.20
EMBIVIL MR 250 mg original250 mg tablet60R287R4.79
Valeptic CR 300300 mg tablet100R489R4.89
Rubilim CR 300300 mg tablet60R294R4.89
Epilizine CR 300300 mg tablet100R669R6.69
Epilim CR 300 original300 mg tablet100R865R8.65
Eprolep CR 500333 mg / 145 mg tablet100R821R8.21
Navalpro CR 500333 mg / 145 mg tablet100R833R8.33
EMBIVIL MR 500 mg original500 mg tablet60R480R8.00
Valeptic CR 500500 mg tablet100R807R8.07
Rubilim CR 500500 mg tablet60R484R8.07
Epilizine CR 500500 mg tablet100R1,107R11.07
Epilim CR 500 original500 mg tablet100R1,539R15.39
Convulex Syrup original50 mg/ml syrup100R178—
Epilim Liquid Sugar Free original200 mg/5ml liquid300R449—
Lepquity250 mg/5ml syrup100R88.48—
Epilim EC 200200 mg gastro-resistant tablet100 tabletsR293R2.93
Epilim EC 500500 mg gastro-resistant tablet100 tabletsR782R7.82
Same medicine, other countries

Valproate 100 mg tablet: South Africa vs 2 other countries

Australia$0.073
United Kingdom$0.075
South Africa (this page)$0.27
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
AustraliaPBS approved ex-manufacturer priceA$0.10$0.073
United KingdomNHS Drug Tariff price£0.056$0.075

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Strengths and forms

Every strength and form of valproate in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
400 mg injection8R76.90—
500 mg modified-release tablet5R480R8.00
300 mg modified-release tablet4R294R4.89
200 mg modified-release tablet3R199R3.31
199.8 mg modified-release tablet2R496R4.96
333 mg modified-release tablet2R821R8.21
100 mg tablet1R446R4.46
150 mg capsule1R375R3.75
300 mg capsule1R750R7.50
500 mg capsule1R1,231R12.31
133.199 mg modified-release tablet1R331R3.31
133.2 mg modified-release tablet1R336R3.36
250 mg modified-release tablet1R287R4.79
50 mg oral liquid1R178—
200 mg oral liquid1R449—

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of valproate in South Africa

16 brand names of valproate are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Valproate manufacturers in South Africa

The official list names 12 manufacturers for valproate in South Africa: Sanofi Aventis South Africa (Pty) Ltd, Acino Pharma (Pty) Ltd, Sandoz SA (Pty) Ltd, Pharmacare Limited, Woodmead, Macleods Pharmaceuticals SA (Pty) Ltd, Abex Pharmaceutica (Pty) Ltd, Kahma Biotech (Pty) Ltd and Ruby Pharmaceuticals (Pty) Ltd and 4 more.

A–Z

Other medicine prices in South Africa

Keep exploring

What people check next

Quick answers

Frequently asked questions

How much does valproate cost in South Africa?
Official SEPs for valproate in South Africa range from R446 to R1,539 per pack across 36 listed products. The cheapest 100 mg tablet works out at R4.46 each (about $0.27).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for valproate at a pharmacy in South Africa?
Up to R652 for Epilim 100 Crushable (100 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest valproate 100 mg tablet in South Africa?
Epilim 100 Crushable at R446 for 100 tablets, or R4.46 per tablet.
What brands of valproate are sold in South Africa?
16 brand names are on the official list, including Cerepiv Iv (from R76.90), Lepquity (from R88.48), Epilizine Intravenous (from R112), Navalpro (from R133) and Convulex (from R178).
Who makes valproate sold in South Africa?
Manufacturers named on the official list include Sanofi Aventis South Africa (Pty) Ltd, Acino Pharma (Pty) Ltd, Sandoz SA (Pty) Ltd and Pharmacare Limited, Woodmead.
Is valproate cheaper in other countries?
For 100 mg tablet, the lowest listed price per tablet is $0.073 in Australia and $0.075 in the United Kingdom, compared with $0.27 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error