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Medicine prices in South Africa

Tipiracil and Trifluridine Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R657

Cheapest 15 mg / 6.14 mg tablet: LONSURF15 mg/6,14 mg, R13,142 for 20 tablets. Official SEP list, Oct 2026.

≈ $39.59 per tablet
R13,142
cheapest pack (20 tablets)
R19,713
30 tablets (1 a day for a month)
2
listed products
SEP
price type
What you actually pay

What a patient pays for tipiracil and trifluridine in South Africa

R13,142
official SEP for LONSURF15 mg/6,14 mg, 20 tablets
+ R1,067
maximum dispensing fee incl. VAT
Up to R14,209
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

2 products

2 different brand names across 2 strengths are on the official list.

Interactive

How much will Tipiracil and Trifluridine 15 mg / 6.14 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R657.10 per tablet.

Estimated cost
R19,713
For a full yearR239,843
Per tablet in USD$39.590
Every listed product

All 2 tipiracil and trifluridine products in South Africa

Tipiracil and Trifluridine official prices in South Africa
ProductStrength and formPackPricePer unit
LONSURF15 mg/6,14 mg original15 mg / 6.14 mg film-coated tablet20 tabletsR13,142R657
LONSURF20 mg/8.19 mg original20 mg / 8.19 mg tablet20 tabletsR17,523R876
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Strengths and forms

Every strength and form of tipiracil and trifluridine in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
15 mg / 6.14 mg tablet1R13,142R657
20 mg / 8.19 mg tablet1R17,523R876

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Who supplies it

Tipiracil and Trifluridine manufacturers in South Africa

The official list names 1 manufacturer for tipiracil and trifluridine in South Africa: Servier Laboratories S.A. (Pty) Ltd.

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Quick answers

Frequently asked questions

How much does tipiracil and trifluridine cost in South Africa?
Official SEPs for tipiracil and trifluridine in South Africa range from R13,142 to R17,523 per pack across 2 listed products. The cheapest 15 mg / 6.14 mg tablet works out at R657 each (about $39.59).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for tipiracil and trifluridine at a pharmacy in South Africa?
Up to R14,209 for LONSURF15 mg/6,14 mg (20 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest tipiracil and trifluridine 15 mg / 6.14 mg tablet in South Africa?
LONSURF15 mg/6,14 mg at R13,142 for 20 tablets, or R657 per tablet.
Who makes tipiracil and trifluridine sold in South Africa?
Manufacturers named on the official list include Servier Laboratories S.A. (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error