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Medicine prices in South Africa

Tacrolimus Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per capsule
R26.80

Cheapest 1 mg capsule: Tarograf 1, R2,680 for 100 capsules. Official SEP list, Oct 2026.

≈ $1.61 per capsule
R2,680
cheapest pack (100 capsules)
R804
30 capsules (1 a day for a month)
36
listed products
SEP
price type
What you actually pay

What a patient pays for tacrolimus in South Africa

R2,680
official SEP for Tarograf 1, 100 capsules
+ R465
maximum dispensing fee incl. VAT
Up to R3,145
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

36 products

31 different brand names across 4 strengths are on the official list.

2.0× spread

For 1 mg capsule, the priciest capsule (Advagraf 1 mg) costs 2.0 times the cheapest (Tarograf 1).

1.8× for the original

The originator brand Prograf 1 mg costs R49.46 per capsule; the cheapest generic, Tarograf 1, costs R26.80.

India

has the lowest listed price per capsule for the same strength: $0.11 vs $1.61 here (different price types; see below).

Interactive

How much will Tacrolimus 1 mg capsule cost you?

capsules per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many capsules you need. This is a cost estimate only, using R26.80 per capsule.

Estimated cost
R804
For a full yearR9,782
Per capsule in USD$1.615
Every listed product

All 36 tacrolimus products in South Africa

Tacrolimus official prices in South Africa
ProductStrength and formPackPricePer unit
Tarograf 11 mg capsule100 capsulesR2,680R26.80
Tacrolimus 1 Teva1 mg capsule30 capsulesR879R29.30
Graftac 11 mg capsule30 capsulesR888R29.60
Talomune 1 mg1 mg capsule30 capsulesR1,290R42.99
TACRUM 1 mg1 mg capsule100 capsulesR4,377R43.77
Tevligraf 11 mg capsule30 capsulesR1,336R44.53
Prograf 1 mg original1 mg capsule100 capsulesR4,946R49.46
Prograf 1 mg original1 mg capsule30 capsulesR1,506R50.19
Advagraf 1 mg original1 mg capsule30 capsulesR1,599R53.29
Tarograf 0.5capsule100 capsulesR1,457R14.57
Tacrolimus 0,5 Teva0.5 mg capsule30 capsulesR481R16.04
Graftac 0,50.5 mg capsule30 capsulesR486R16.21
Talomune 0,5 mg0.5 mg capsule30 capsulesR662R22.06
TACRUM 0,5 mg0.5 mg capsule50 capsulesR1,201R24.02
Tevligraf 0,50.5 mg capsule30 capsulesR733R24.43
Prograf 0,5 mg original0.5 mg capsule50 capsulesR1,354R27.08
Prograf 0,5 mg original0.5 mg capsule30 capsulesR824R27.48
Advagraf 0,5 mg original0.5 mg capsule30 capsulesR877R29.25
Tarograf 55 mg capsule100 capsulesR12,961R130
Tacrolimus 5 Teva5 mg capsule30 capsulesR4,251R142
Graftac 55 mg capsule30 capsulesR4,294R143
Talomune 5 mg5 mg capsule30 capsulesR5,968R199
TACRUM 5 mg5 mg capsule50 capsulesR10,648R213
Tevligraf 55 mg capsule30 capsulesR6,500R217
Prograf 5 mg original5 mg capsule50 capsulesR11,959R239
Prograf 5 mg original5 mg capsule30 capsulesR7,281R243
Advagraf 5 mg original5 mg capsule30 capsulesR7,779R259
Graftac 0,5 Prolonged Release0.5 mg capsule30R500R16.67
Graftac 1 Prolonged Release1 mg capsule30R911R30.38
Graftac 5 Prolonged Release5 mg capsule30R4,435R148
CLERAGLEN 0.03 %0.3 mg/g ointment30R420—
Protopic 0,03% Ointment original0.3 mg/g ointment30R466—
Protopic 0,03% Ointment original0.3 mg/g ointment60R932—
CLERAGLEN 0,1 %1 mg/g ointment30R465—
Protopic 0,1% Ointment original1 mg/g ointment30R517—
Protopic 0,1% Ointment original1 mg/g ointment60R1,033—
Tarograf 1R26.80
Tacrolimus 1 TevaR29.30
Graftac 1R29.60
Talomune 1 mgR42.99
TACRUM 1 mgR43.77
Tevligraf 1R44.53
Prograf 1 mgR49.46
Advagraf 1 mgR53.29
Tacrolimus 1 mg capsule: price per capsule by product (ZAR)
Same medicine, other countries

Tacrolimus 1 mg capsule: South Africa vs 5 other countries

India$0.11
United States$0.16
Australia$0.75
United Arab Emirates$1.32
South Africa (this page)$1.61
United Kingdom$2.15
Lowest listed price per capsule (USD)
By country
CountryPrice typePer capsule (local)Per unit (USD)
IndiaJan Aushadhi MRP₹10.31$0.11
United StatesNADAC pharmacy acquisition cost$0.16$0.16
AustraliaPBS approved ex-manufacturer priceA$1.07$0.75
United Arab EmiratesAbu Dhabi DoH public priceAED 4.85$1.32
United KingdomNHS Drug Tariff price£1.61$2.15

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Other medicines with tacrolimus
Strengths and forms

Every strength and form of tacrolimus in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
1 mg capsule9R879R26.80
5 mg capsule9R4,251R130
0.5 mg capsule8R481R16.04
0.3 mg ointment3R420—
1 mg ointment3R465—
capsule1R1,457R14.57
0.5 mg modified-release capsule1R500R16.67
1 mg modified-release capsule1R911R30.38
5 mg modified-release capsule1R4,435R148

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of tacrolimus in South Africa

9 brand names of tacrolimus are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Tacrolimus manufacturers in South Africa

The official list names 8 manufacturers for tacrolimus in South Africa: Accord Healthcare (Pty) Ltd, Teva Pharmaceuticals (Pty) Ltd, Sandoz SA (Pty) Ltd, Strides Pharma SA (Pty) Ltd, Cipla Medpro (Pty) Ltd, Astellas Pharma (Pty) Ltd, Glenmark Pharmaceuticals South Africa (Pty) Ltd and Adcock Ingram Limited.

A–Z

Other medicine prices in South Africa

Keep exploring

What people check next

Quick answers

Frequently asked questions

How much does tacrolimus cost in South Africa?
Official SEPs for tacrolimus in South Africa range from R879 to R12,961 per pack across 36 listed products. The cheapest 1 mg capsule works out at R26.80 each (about $1.61).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for tacrolimus at a pharmacy in South Africa?
Up to R3,145 for Tarograf 1 (100 capsules). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest tacrolimus 1 mg capsule in South Africa?
Tarograf 1 at R2,680 for 100 capsules, or R26.80 per capsule. 8 other products have the same strength.
What brands of tacrolimus are sold in South Africa?
9 brand names are on the official list, including Cleraglen (from R420), Protopic (from R466), Graftac (from R486), Talomune (from R662) and Tevligraf (from R733).
Who makes tacrolimus sold in South Africa?
Manufacturers named on the official list include Accord Healthcare (Pty) Ltd, Teva Pharmaceuticals (Pty) Ltd, Sandoz SA (Pty) Ltd and Strides Pharma SA (Pty) Ltd.
Is tacrolimus cheaper in other countries?
For 1 mg capsule, the lowest listed price per capsule is $0.11 in India, $0.16 in the United States, $0.75 in Australia and $1.32 in the UAE, compared with $1.61 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error