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Medicine prices in South Africa

Sulfamethoxazole and Trimethoprin Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R6.85

Cheapest pack: Xerazole Suspension, 200 mg/5ml / 40 mg/5ml suspension, 50. Official SEP list, Oct 2026.

≈ $0.41
R6.85 – R68.59
per pack
1
strength
3
listed products
SEP
price type
What you actually pay

What a patient pays for sulfamethoxazole and trimethoprin in South Africa

R6.85
official SEP for Xerazole Suspension, 50
+ R30.22
maximum dispensing fee incl. VAT
Up to R37.07
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

3 products

One product name across 1 strength are on the official list.

Every listed product

All 3 sulfamethoxazole and trimethoprin products in South Africa

Sulfamethoxazole and Trimethoprin official prices in South Africa
ProductStrength and formPackPricePer unit
Xerazole Suspension200 mg/5ml / 40 mg/5ml suspension50R6.85—
Xerazole Suspension200 mg/5ml / 40 mg/5ml suspension100R13.73—
Xerazole Suspension200 mg/5ml / 40 mg/5ml suspension499.6R68.59—
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Brand names

Brands of sulfamethoxazole and trimethoprin in South Africa

1 brand name of sulfamethoxazole and trimethoprin is on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Sulfamethoxazole and Trimethoprin manufacturers in South Africa

The official list names 1 manufacturer for sulfamethoxazole and trimethoprin in South Africa: F.D.C. SA (PTY) LTD.

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Quick answers

Frequently asked questions

How much does sulfamethoxazole and trimethoprin cost in South Africa?
Official SEPs for sulfamethoxazole and trimethoprin in South Africa range from R6.85 to R68.59 per pack across 3 listed products.
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for sulfamethoxazole and trimethoprin at a pharmacy in South Africa?
Up to R37.07 for Xerazole Suspension (50). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What brands of sulfamethoxazole and trimethoprin are sold in South Africa?
1 brand name is on the official list, including Xerazole (from R6.85).
Who makes sulfamethoxazole and trimethoprin sold in South Africa?
Manufacturers named on the official list include F.D.C. SA (PTY) LTD.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error