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Medicine prices in South Africa

Sofosbuvir and Velpatasvir Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R400

Cheapest 400 mg / 100 mg tablet: EPCLUSA, R11,211 for 28 tablets. Official SEP list, Oct 2026.

≈ $24.12 per tablet
R11,211
cheapest pack (28 tablets)
R12,011
30 tablets (1 a day for a month)
1
listed product
SEP
price type
What you actually pay

What a patient pays for sofosbuvir and velpatasvir in South Africa

R11,211
official SEP for EPCLUSA, 28 tablets
+ R956
maximum dispensing fee incl. VAT
Up to R12,166
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

Interactive

How much will Sofosbuvir and Velpatasvir 400 mg / 100 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R400.38 per tablet.

Estimated cost
R12,011
For a full yearR146,140
Per tablet in USD$24.123
Every listed product

All 1 sofosbuvir and velpatasvir product in South Africa

Sofosbuvir and Velpatasvir official prices in South Africa
ProductStrength and formPackPricePer unit
EPCLUSA original400 mg / 100 mg film-coated tablet28 tabletsR11,211R400
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Brand names

Brands of sofosbuvir and velpatasvir in South Africa

1 brand name of sofosbuvir and velpatasvir is on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Sofosbuvir and Velpatasvir manufacturers in South Africa

The official list names 1 manufacturer for sofosbuvir and velpatasvir in South Africa: Gilead Sciences South Africa (Pty) Ltd.

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Quick answers

Frequently asked questions

How much does sofosbuvir and velpatasvir cost in South Africa?
Official SEPs for sofosbuvir and velpatasvir in South Africa range from R11,211 to R11,211 per pack across 1 listed product. The cheapest 400 mg / 100 mg tablet works out at R400 each (about $24.12).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for sofosbuvir and velpatasvir at a pharmacy in South Africa?
Up to R12,166 for EPCLUSA (28 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest sofosbuvir and velpatasvir 400 mg / 100 mg tablet in South Africa?
EPCLUSA at R11,211 for 28 tablets, or R400 per tablet.
What brands of sofosbuvir and velpatasvir are sold in South Africa?
1 brand name is on the official list, including Epclusa (from R11,211).
Who makes sofosbuvir and velpatasvir sold in South Africa?
Manufacturers named on the official list include Gilead Sciences South Africa (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error