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Medicine prices in South Africa

Sacubitril and Valsartan Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R14.71

Cheapest 24 mg / 26 mg tablet: SACUVAN 24 mg/26 mg, R441 for 30 tablets. Official SEP list, Oct 2026.

≈ $0.89 per tablet
R441
cheapest pack (30 tablets)
R441
30 tablets (1 a day for a month)
9
listed products
SEP
price type
What you actually pay

What a patient pays for sacubitril and valsartan in South Africa

R441
official SEP for SACUVAN 24 mg/26 mg, 30 tablets
+ R206
maximum dispensing fee incl. VAT
Up to R647
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

9 products

9 different brand names across 6 strengths are on the official list.

1.4× spread

For 24 mg / 26 mg tablet, the priciest tablet (Vymada 50 mg) costs 1.4 times the cheapest (SACUVAN 24 mg/26 mg).

India

has the lowest listed price per tablet for the same strength: $0.071 vs $0.89 here (different price types; see below).

Interactive

How much will Sacubitril and Valsartan 24 mg / 26 mg tablet cost you?

tablets per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many tablets you need. This is a cost estimate only, using R14.71 per tablet.

Estimated cost
R441
For a full yearR5,369
Per tablet in USD$0.886
Every listed product

All 9 sacubitril and valsartan products in South Africa

Sacubitril and Valsartan official prices in South Africa
ProductStrength and formPackPricePer unit
SACUVAN 24 mg/26 mg24 mg / 26 mg film-coated tablet30 tabletsR441R14.71
Vymada 50 mg24 mg / 26 mg tablet28 tabletsR557R19.90
Arnizyd 26/2426/24 tablet30 tabletsR298R9.94
SACUVAN 49 mg/51 mg49 mg / 51 mg film-coated tablet30 tabletsR441R14.71
Vymada 100 mg49 mg / 51 mg tablet28 tabletsR557R19.90
Arnizyd 51/4951/49 tablet30 tabletsR368R12.27
SACUVAN 97 mg/103 mg97 mg / 103 mg film-coated tablet30 tabletsR441R14.71
Vymada 200 mg97 mg / 103 mg tablet28 tabletsR557R19.90
Arnizyd 103/97103/97 tablet30 tabletsR438R14.59
SACUVAN 24 mg/26 mgR14.71
Vymada 50 mgR19.90
Sacubitril and Valsartan 24 mg / 26 mg tablet: price per tablet by product (ZAR)
Same medicine, other countries

Sacubitril and Valsartan 24 mg / 26 mg tablet: South Africa vs India

India$0.071
South Africa (this page)$0.89
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹6.75$0.071

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Strengths and forms

Every strength and form of sacubitril and valsartan in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
24 mg / 26 mg tablet2R441R14.71
49 mg / 51 mg tablet2R441R14.71
97 mg / 103 mg tablet2R441R14.71
26/24 tablet1R298R9.94
51/49 tablet1R368R12.27
103/97 tablet1R438R14.59

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of sacubitril and valsartan in South Africa

3 brand names of sacubitril and valsartan are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Sacubitril and Valsartan manufacturers in South Africa

The official list names 3 manufacturers for sacubitril and valsartan in South Africa: Hetero Drugs South Africa (Pty) Ltd, Novartis South Africa (Pty) Ltd and Zydus Healthcare SA (Pty) Ltd.

A–Z

Other medicine prices in South Africa

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Quick answers

Frequently asked questions

How much does sacubitril and valsartan cost in South Africa?
Official SEPs for sacubitril and valsartan in South Africa range from R441 to R557 per pack across 9 listed products. The cheapest 24 mg / 26 mg tablet works out at R14.71 each (about $0.89).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for sacubitril and valsartan at a pharmacy in South Africa?
Up to R647 for SACUVAN 24 mg/26 mg (30 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest sacubitril and valsartan 24 mg / 26 mg tablet in South Africa?
SACUVAN 24 mg/26 mg at R441 for 30 tablets, or R14.71 per tablet. 1 other product has the same strength.
What brands of sacubitril and valsartan are sold in South Africa?
3 brand names are on the official list, including Arnizyd (from R298), Sacuvan (from R441) and Vymada (from R557).
Who makes sacubitril and valsartan sold in South Africa?
Manufacturers named on the official list include Hetero Drugs South Africa (Pty) Ltd, Novartis South Africa (Pty) Ltd and Zydus Healthcare SA (Pty) Ltd.
Is sacubitril and valsartan cheaper in other countries?
For 24 mg / 26 mg tablet, the lowest listed price per tablet is $0.071 in India, compared with $0.89 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error