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Medicine prices in South Africa

Nirmatrelvir and Ritonavir Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R447

Cheapest 150 mg / 100 tablet: Paxlovid, R13,411 for 30 tablets. Official SEP list, Oct 2026.

≈ $26.93 per tablet
R13,411
cheapest pack (30 tablets)
R13,411
30 tablets (1 a day for a month)
1
listed product
SEP
price type
What you actually pay

What a patient pays for nirmatrelvir and ritonavir in South Africa

R13,411
official SEP for Paxlovid, 30 tablets
+ R1,082
maximum dispensing fee incl. VAT
Up to R14,493
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

Interactive

How much will Nirmatrelvir and Ritonavir 150 mg / 100 tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R447.03 per tablet.

Estimated cost
R13,411
For a full yearR163,165
Per tablet in USD$26.933
Every listed product

All 1 nirmatrelvir and ritonavir product in South Africa

Nirmatrelvir and Ritonavir official prices in South Africa
ProductStrength and formPackPricePer unit
Paxlovid original150 mg / 100 film-coated tablet30 tabletsR13,411R447
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Brand names

Brands of nirmatrelvir and ritonavir in South Africa

1 brand name of nirmatrelvir and ritonavir is on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Nirmatrelvir and Ritonavir manufacturers in South Africa

The official list names 1 manufacturer for nirmatrelvir and ritonavir in South Africa: Pfizer Laboratories (Pty) Ltd.

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Quick answers

Frequently asked questions

How much does nirmatrelvir and ritonavir cost in South Africa?
Official SEPs for nirmatrelvir and ritonavir in South Africa range from R13,411 to R13,411 per pack across 1 listed product. The cheapest 150 mg / 100 tablet works out at R447 each (about $26.93).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for nirmatrelvir and ritonavir at a pharmacy in South Africa?
Up to R14,493 for Paxlovid (30 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest nirmatrelvir and ritonavir 150 mg / 100 tablet in South Africa?
Paxlovid at R13,411 for 30 tablets, or R447 per tablet.
What brands of nirmatrelvir and ritonavir are sold in South Africa?
1 brand name is on the official list, including Paxlovid (from R13,411).
Who makes nirmatrelvir and ritonavir sold in South Africa?
Manufacturers named on the official list include Pfizer Laboratories (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error