Naproxen Price in the United States (2026)
Average pharmacy cost for generic naproxen 375 mg tablet, across 14 product codes (NDCs). CMS NADAC file, Oct 2026.
≈ $0.058 per tabletNaproxen cost without insurance
The figures here are what US retail pharmacies pay for generic naproxen: about $0.058 per tablet (375 mg tablet), so $1.73 for a 30-day supply at one a day. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.
With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.
One product name across 6 strengths are on the official list.
For 375 mg tablet, the priciest tablet (naproxen dr 375 mg tablet) costs 37.4 times the cheapest (naproxen 375 mg tablet).
How much will Naproxen 375 mg tablet cost you?
All 10 naproxen products in the United States
| Generic (NADAC description) | Strength | Form | Per unit | 30 units |
|---|---|---|---|---|
| naproxen 375 mg tablet | 375 mg | tablet | $0.058 | $1.73 |
| naproxen dr 375 mg tablet | 375 mg | tablet | $2.16 | $64.74 |
| naproxen sod cr 500 mg tablet | 500 mg | modified-release tablet | $8.78 | $263 |
| naproxen sod er 500 mg tablet | 500 mg | modified-release tablet | $8.78 | $263 |
| naproxen 125 mg/5 mL suspen | 125 mg | other | $0.21 | $6.28 |
| naproxen 250 mg tablet | 250 mg | tablet | $0.050 | $1.49 |
| naproxen sodium 275 mg tab | 275 mg | tablet | $0.20 | $5.88 |
| naproxen 500 mg tablet | 500 mg | tablet | $0.058 | $1.73 |
| naproxen dr 500 mg tablet | 500 mg | tablet | $1.95 | $58.41 |
| naproxen sodium 550 mg tab | 550 mg | tablet | $0.22 | $6.46 |
Naproxen 375 mg tablet: the United States vs the United Kingdom
| Country | Price type | Per tablet (local) | Per unit (USD) |
|---|---|---|---|
| United Kingdom | NHS Drug Tariff price | £0.13 | $0.17 |
Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at ECB reference rates of 23 October 2026.
How NADAC prices work in the United States
Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
Read the full guide to medicine prices in the United States.
Combinations containing naproxen in the United States
Every strength and form of naproxen in the United States
| Strength and form | Products | Cheapest pack | Cheapest per unit |
|---|---|---|---|
| 375 mg tablet | 2 | $0.058 | $0.058 |
| 500 mg modified-release tablet | 2 | $8.78 | $8.78 |
| 500 mg tablet | 2 | $0.058 | $0.058 |
| 125 mg other | 1 | $0.21 | — |
| 250 mg tablet | 1 | $0.050 | $0.050 |
| 275 mg tablet | 1 | $0.20 | $0.20 |
| 550 mg tablet | 1 | $0.22 | $0.22 |
Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.
Other medicine prices in the United States
What people check next
Frequently asked questions
How much does naproxen cost in the United States?
What kind of price is this?
What is the cheapest naproxen 375 mg tablet in the United States?
How much does naproxen cost without insurance?
Is NADAC the retail price of naproxen?
Is naproxen cheaper in other countries?
Sources
- Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
- European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.
Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error