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Medicine prices in South Africa

Melatonin Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R10.21

Cheapest 2 mg tablet: Cadiatev, R306 for 30 tablets. Official SEP list, Oct 2026.

≈ $0.62 per tablet
R306
cheapest pack (30 tablets)
R306
30 tablets (1 a day for a month)
5
listed products
SEP
price type
What you actually pay

What a patient pays for melatonin in South Africa

R306
official SEP for Cadiatev, 30 tablets
+ R166
maximum dispensing fee incl. VAT
Up to R472
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

5 products

5 different brand names across 1 strength are on the official list.

1.5× spread

For 2 mg tablet, the priciest tablet (Circadin 2 mg) costs 1.5 times the cheapest (Cadiatev).

1.2× for the original

The originator brand VIGISOM costs R11.79 per tablet; the cheapest generic, Cadiatev, costs R10.21.

United Kingdom

has the lowest listed price per tablet for the same strength: $0.49 vs $0.62 here (different price types; see below).

Interactive

How much will Melatonin 2 mg tablet cost you?

tablets per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many tablets you need. This is a cost estimate only, using R10.21 per tablet.

Estimated cost
R306
For a full yearR3,726
Per tablet in USD$0.615
Every listed product

All 5 melatonin products in South Africa

Melatonin official prices in South Africa
ProductStrength and formPackPricePer unit
Cadiatev2 mg tablet30 tabletsR306R10.21
VIGISOM original2 mg tablet30 tabletsR354R11.79
Circadin 2 mg original2 mg tablet30 tabletsR445R14.84
Melnoc XR 2 mg2 mg tablet30R331R11.04
Noctrin XR 2 mg2 mg tablet30R378R12.59
CadiatevR10.21
VIGISOMR11.79
Circadin 2 mgR14.84
Melatonin 2 mg tablet: price per tablet by product (ZAR)
Same medicine, other countries

Melatonin 2 mg tablet: South Africa vs the United Kingdom

United Kingdom$0.49
South Africa (this page)$0.62
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
United KingdomNHS Drug Tariff price£0.36$0.49

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Strengths and forms

Every strength and form of melatonin in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
2 mg tablet3R306R10.21
2 mg modified-release tablet2R331R11.04

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of melatonin in South Africa

5 brand names of melatonin are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Melatonin manufacturers in South Africa

The official list names 3 manufacturers for melatonin in South Africa: Teva Pharmaceuticals (Pty) Ltd, Acino Pharma (Pty) Ltd and Trinity Pharma (Pty) Ltd.

A–Z

Other medicine prices in South Africa

Keep exploring

What people check next

Quick answers

Frequently asked questions

How much does melatonin cost in South Africa?
Official SEPs for melatonin in South Africa range from R306 to R445 per pack across 5 listed products. The cheapest 2 mg tablet works out at R10.21 each (about $0.62).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for melatonin at a pharmacy in South Africa?
Up to R472 for Cadiatev (30 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest melatonin 2 mg tablet in South Africa?
Cadiatev at R306 for 30 tablets, or R10.21 per tablet. 2 other products have the same strength.
What brands of melatonin are sold in South Africa?
5 brand names are on the official list, including Cadiatev (from R306), Melnoc (from R331), Vigisom (from R354), Noctrin (from R378) and Circadin (from R445).
Who makes melatonin sold in South Africa?
Manufacturers named on the official list include Teva Pharmaceuticals (Pty) Ltd, Acino Pharma (Pty) Ltd and Trinity Pharma (Pty) Ltd.
Is melatonin cheaper in other countries?
For 2 mg tablet, the lowest listed price per tablet is $0.49 in the United Kingdom, compared with $0.62 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error