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Medicine prices in South Africa

Hydrochlorothiazide Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R0.62

Cheapest 25 mg tablet: ZIDAFLO 25, R61.72 for 100 tablets. Official SEP list, Oct 2026.

≈ $0.037 per tablet
R61.72
cheapest pack (100 tablets)
R18.52
30 tablets (1 a day for a month)
10
listed products
SEP
price type
What you actually pay

What a patient pays for hydrochlorothiazide in South Africa

R61.72
official SEP for ZIDAFLO 25, 100 tablets
+ R59.25
maximum dispensing fee incl. VAT
Up to R121
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

10 products

7 different brand names across 2 strengths are on the official list.

2.8× spread

For 25 mg tablet, the priciest tablet (Renezide) costs 2.8 times the cheapest (ZIDAFLO 25).

India

has the lowest listed price per tablet for the same strength: $0.009 vs $0.037 here (different price types; see below).

Interactive

How much will Hydrochlorothiazide 25 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using R0.617 per tablet.

Estimated cost
R18.52
For a full yearR225
Per tablet in USD$0.037
Every listed product

All 10 hydrochlorothiazide products in South Africa

Hydrochlorothiazide official prices in South Africa
ProductStrength and formPackPricePer unit
ZIDAFLO 2525 mg tablet100 tabletsR61.72R0.62
Gulf Hydrochlorothiazide 2525 mg tablet30 tabletsR18.76R0.63
Gulf Hydrochlorothiazide 2525 mg tablet100 tabletsR62.54R0.63
Gulf Hydrochlorothiazide 2525 mg tablet500 tabletsR313R0.63
Hexazide 2525 mg tablet100 tabletsR65.46R0.65
Ridaq-2525 mg tablet500 tabletsR724R1.45
Renezide25 mg tablet250 tabletsR430R1.72
Renezide25 mg tablet28 tabletsR48.20R1.72
Zidaflo 12,512,5 tablet30 tabletsR16.36R0.55
Ridaq12.5 mg tablet30 tabletsR19.94R0.66
ZIDAFLO 25R0.62
Gulf Hydrochlorothiazide 25R0.63
Hexazide 25R0.65
Ridaq-25R1.45
RenezideR1.72
Hydrochlorothiazide 25 mg tablet: price per tablet by product (ZAR)
Same medicine, other countries

Hydrochlorothiazide 25 mg tablet: South Africa vs 4 other countries

India$0.009
United States$0.011
United Arab Emirates$0.037
South Africa (this page)$0.037
Australia$0.053
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
IndiaJan Aushadhi MRP₹0.84$0.009
United StatesNADAC pharmacy acquisition cost$0.011$0.011
United Arab EmiratesAbu Dhabi DoH public priceAED 0.13$0.037
AustraliaPBS approved ex-manufacturer priceA$0.076$0.053

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Other medicines with hydrochlorothiazide
Strengths and forms

Every strength and form of hydrochlorothiazide in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
25 mg tablet8R18.76R0.62
tablet1R16.36R0.55
12.5 mg tablet1R19.94R0.66

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of hydrochlorothiazide in South Africa

4 brand names of hydrochlorothiazide are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Hydrochlorothiazide manufacturers in South Africa

The official list names 5 manufacturers for hydrochlorothiazide in South Africa: Austell Pharmaceuticals (Pty) Ltd, Gulf Drug Company (Pty) Ltd, Sandoz SA (Pty) Ltd, Pharmacare Limited, Woodmead and Litha Pharma (Pty) Ltd.

A–Z

Other medicine prices in South Africa

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What people check next

Quick answers

Frequently asked questions

How much does hydrochlorothiazide cost in South Africa?
Official SEPs for hydrochlorothiazide in South Africa range from R18.76 to R724 per pack across 10 listed products. The cheapest 25 mg tablet works out at R0.62 each (about $0.037).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for hydrochlorothiazide at a pharmacy in South Africa?
Up to R121 for ZIDAFLO 25 (100 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest hydrochlorothiazide 25 mg tablet in South Africa?
ZIDAFLO 25 at R61.72 for 100 tablets, or R0.62 per tablet. 7 other products have the same strength.
What brands of hydrochlorothiazide are sold in South Africa?
4 brand names are on the official list, including Zidaflo (from R16.36), Ridaq (from R19.94), Renezide (from R48.20) and Hexazide (from R65.46).
Who makes hydrochlorothiazide sold in South Africa?
Manufacturers named on the official list include Austell Pharmaceuticals (Pty) Ltd, Gulf Drug Company (Pty) Ltd, Sandoz SA (Pty) Ltd and Pharmacare Limited, Woodmead.
Is hydrochlorothiazide cheaper in other countries?
For 25 mg tablet, the lowest listed price per tablet is $0.009 in India, $0.011 in the United States, $0.037 in the UAE and $0.053 in Australia, compared with $0.037 in South Africa. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error