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Medicine prices in South Africa

Fentanyl Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R1,564

Cheapest pack: Adco Tenyl 100µg/h, 100 µg/h patch, 5. Official SEP list, Oct 2026.

≈ $94.20
R119 – R2,606
per pack
8
strengths
20
listed products
SEP
price type
What you actually pay

What a patient pays for fentanyl in South Africa

R1,564
official SEP for Adco Tenyl 100µg/h, 5
+ R401
maximum dispensing fee incl. VAT
Up to R1,965
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

20 products

20 different brand names across 8 strengths are on the official list.

Every listed product

All 20 fentanyl products in South Africa

Fentanyl official prices in South Africa
ProductStrength and formPackPricePer unit
Adco Tenyl 100µg/h100 µg/h patch5R1,564—
Fendermal 100µg/h100 µg/h patch5R1,800—
EFFENTORA 100 original100 ug effervescent tablet28R1,985R70.88
EFFENTORA 200 original200 ug effervescent tablet28R1,985R70.88
EFFENTORA 400 original400 ug effervescent tablet28R1,985R70.88
Sublimaze 2ml original50 mcg/ml injection10R445—
Sublimaze 10ml original50 mcg/ml injection50R2,226—
Pharma-Q Fentanyl 100mcg/2 ml Injection100 mcg/2ml injection10R119—
Pharma-Q Fentanyl 500mcg/10ml Injection500 mcg/10ml injection10R198—
Durogesic 12Mcg Per Hour original12 mcg pad5R394—
Durogesic 25Mcg Per Hour original25 mcg pad5R893—
Durogesic 50Mcg Per Hour original50 mcg pad5R1,478—
Durogesic 75Mcg Per Hour original75 mcg pad5R2,036—
Durogesic 100Mcg Per Hour original100 mcg pad5R2,606—
Adco Tenyl 25µg/h25 µg/h patch5R536—
Fendermal 25µg/h25 µg/h patch5R604—
Adco Tenyl 50µg/h50 µg/h patch5R887—
Fendermal 50µg/h50 µg/h patch5R1,010—
Adco Tenyl 75µg/h75 µg/h patch5R1,221—
Fendermal 75µg/h75 µg/h patch5R1,399—
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Strengths and forms

Every strength and form of fentanyl in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
100 mcg patch2R1,564—
50 mcg injection2R445—
25 mcg patch2R536—
50 mcg patch2R887—
75 mcg patch2R1,221—
100 mcg effervescent tablet1R1,985R70.88
200 mcg effervescent tablet1R1,985R70.88
400 mcg effervescent tablet1R1,985R70.88
100 mcg injection1R119—
500 mcg injection1R198—
12 mcg other1R394—
25 mcg other1R893—
50 mcg other1R1,478—
75 mcg other1R2,036—
100 mcg other1R2,606—

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of fentanyl in South Africa

5 brand names of fentanyl are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Fentanyl manufacturers in South Africa

The official list names 6 manufacturers for fentanyl in South Africa: Adcock Ingram Limited, Sandoz SA (Pty) Ltd, Teva Pharmaceuticals (Pty) Ltd, Piramal Critical Care South Africa (Pty) Ltd, Pharma-Q Holdings (Pty) Ltd and Janssen Pharmaceutica (Pty) Ltd.

A–Z

Other medicine prices in South Africa

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Quick answers

Frequently asked questions

How much does fentanyl cost in South Africa?
Official SEPs for fentanyl in South Africa range from R1,564 to R2,606 per pack across 20 listed products.
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for fentanyl at a pharmacy in South Africa?
Up to R1,965 for Adco Tenyl 100µg/h (5). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What brands of fentanyl are sold in South Africa?
5 brand names are on the official list, including Durogesic (from R394), Sublimaze (from R445), Adco Tenyl (from R536), Fendermal (from R604) and Effentora (from R1,985).
Who makes fentanyl sold in South Africa?
Manufacturers named on the official list include Adcock Ingram Limited, Sandoz SA (Pty) Ltd, Teva Pharmaceuticals (Pty) Ltd and Piramal Critical Care South Africa (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error