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Medicine prices in South Africa

Ezetimibe and Simvastatin Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R6.58

Cheapest 10 mg / 10 mg tablet: Tryzetor Plus 10/10 mg, R198 for 30 tablets. Official SEP list, Oct 2026.

≈ $0.40 per tablet
R198
cheapest pack (30 tablets)
R198
30 tablets (1 a day for a month)
20
listed products
SEP
price type
What you actually pay

What a patient pays for ezetimibe and simvastatin in South Africa

R198
official SEP for Tryzetor Plus 10/10 mg, 30 tablets
+ R124
maximum dispensing fee incl. VAT
Up to R322
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

20 products

20 different brand names across 5 strengths are on the official list.

1.4× for the original

The originator brand INEGY 10/10 costs R9.37 per tablet; the cheapest generic, Tryzetor Plus 10/10 mg, costs R6.58.

Interactive

How much will Ezetimibe and Simvastatin 10 mg / 10 mg tablet cost you?

tablets per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many tablets you need. This is a cost estimate only, using R6.58 per tablet.

Estimated cost
R198
For a full yearR2,403
Per tablet in USD$0.397
Every listed product

All 20 ezetimibe and simvastatin products in South Africa

Ezetimibe and Simvastatin official prices in South Africa
ProductStrength and formPackPricePer unit
Tryzetor Plus 10/10 mg10 mg / 10 mg tablet30 tabletsR198R6.58
Ezetimibe simvastatin 10mg/10 mg Alkem10 mg / 10 mg tablet30 tabletsR201R6.69
Ezimva 10/1010 mg / 10 mg tablet30 tabletsR205R6.83
MEZIBE PLUS 10/1010 mg / 10 mg tablet30 tabletsR205R6.84
Ezesim 10/1010 mg / 10 mg tablet30 tabletsR205R6.84
INEGY 10/10 original10 mg / 10 mg tablet30 tabletsR281R9.37
Simezyd 10/2010 mg / 20 mg tablet30 tabletsR193R6.43
Simezyd 10/4010 mg / 40 mg tablet30 tabletsR193R6.43
Tryzetor Plus 10/20 mg10 mg / 20 mg tablet30 tabletsR198R6.58
Tryzetor Plus 10/40 mg10 mg / 40 mg tablet30 tabletsR198R6.58
Ezetimibe simvastatin 10mg/20 mg Alkem10 mg / 20 mg tablet30 tabletsR201R6.69
Ezetimibe simvastatin 10mg/40 mg Alkem10 mg / 40 mg tablet30 tabletsR201R6.69
Ezimva 10/2010 mg / 20 mg tablet30 tabletsR205R6.83
Ezimva 10/4010 mg / 40 mg tablet30 tabletsR205R6.83
MEZIBE PLUS 10/2010 mg / 20 mg tablet30 tabletsR205R6.84
MEZIBE PLUS 10/4010 mg / 40 mg tablet30 tabletsR205R6.84
Ezesim 10/2010 mg / 20 mg tablet30 tabletsR205R6.84
Ezesim 10/4010 mg / 40 mg tablet30 tabletsR205R6.84
INEGY 10/20 original20 mg / 10 mg tablet30 tabletsR281R9.37
INEGY 10/40 original40 mg / 10 mg tablet30 tabletsR281R9.37
Tryzetor Plus 10/10 mgR6.58
Ezetimibe simvastatin 10mg/10 mg AlkemR6.69
Ezimva 10/10R6.83
MEZIBE PLUS 10/10R6.84
Ezesim 10/10R6.84
INEGY 10/10R9.37
Ezetimibe and Simvastatin 10 mg / 10 mg tablet: price per tablet by product (ZAR)
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Strengths and forms

Every strength and form of ezetimibe and simvastatin in South Africa

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
10 mg / 10 mg tablet6R198R6.58
10 mg / 20 mg tablet6R193R6.43
10 mg / 40 mg tablet6R193R6.43
20 mg / 10 mg tablet1R281R9.37
40 mg / 10 mg tablet1R281R9.37

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

Brand names

Brands of ezetimibe and simvastatin in South Africa

6 brand names of ezetimibe and simvastatin are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Ezetimibe and Simvastatin manufacturers in South Africa

The official list names 6 manufacturers for ezetimibe and simvastatin in South Africa: Pharma Dynamics (Pty) Ltd, Ascend Laboratories (Pty) Ltd, Ranbaxy Pharmaceuticals (Pty) Ltd, Forrester Pharma (Pty) Ltd, Organon South Africa (Pty) Ltd and Zydus Healthcare SA (Pty) Ltd.

A–Z

Other medicine prices in South Africa

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What people check next

Quick answers

Frequently asked questions

How much does ezetimibe and simvastatin cost in South Africa?
Official SEPs for ezetimibe and simvastatin in South Africa range from R198 to R281 per pack across 20 listed products. The cheapest 10 mg / 10 mg tablet works out at R6.58 each (about $0.40).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for ezetimibe and simvastatin at a pharmacy in South Africa?
Up to R322 for Tryzetor Plus 10/10 mg (30 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest ezetimibe and simvastatin 10 mg / 10 mg tablet in South Africa?
Tryzetor Plus 10/10 mg at R198 for 30 tablets, or R6.58 per tablet. 5 other products have the same strength.
What brands of ezetimibe and simvastatin are sold in South Africa?
6 brand names are on the official list, including Simezyd (from R193), Tryzetor (from R198), Ezimva (from R205), Mezibe (from R205) and Ezesim (from R205).
Who makes ezetimibe and simvastatin sold in South Africa?
Manufacturers named on the official list include Pharma Dynamics (Pty) Ltd, Ascend Laboratories (Pty) Ltd, Ranbaxy Pharmaceuticals (Pty) Ltd and Forrester Pharma (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error