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Medicine prices in the United States

Donepezil Price in the United States (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 31 October 2026How we get our data
Lowest NADAC pharmacy acquisition cost per tablet
$0.049

Average pharmacy cost for generic donepezil 10 mg tablet, across 27 product codes (NDCs). CMS NADAC file, Oct 2026.

≈ $0.049 per tablet
$1.47
30 tablets (pharmacy cost)
$4.40
90 tablets (pharmacy cost)
5
strengths and forms
NADAC
price type (CMS)
Cash price

Donepezil cost without insurance

The figures here are what US retail pharmacies pay for generic donepezil: about $0.049 per tablet (10 mg tablet), so $1.47 for a 30-day supply at one a day. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.

With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.

5 products

One product name across 3 strengths are on the official list.

United Kingdom

has the lowest listed price per tablet for the same strength: $0.046 vs $0.049 here (different price types; see below).

Interactive

How much will Donepezil 10 mg tablet cost you?

tablets per day: 1 a day

Your doctor decides how many tablets you need. This is a cost estimate only, using $0.049 per tablet.

Estimated cost
$1.47
For a full year$17.85
Every listed product

All 5 donepezil products in the United States

Donepezil official prices in the United States
Generic (NADAC description)StrengthFormPer unit30 units
donepezil hcl 10 mg tablet10 mgtablet$0.049$1.47
donepezil hcl odt 5 mg tablet5 mgorodispersible tablet$0.28$8.29
donepezil hcl odt 10 mg tablet10 mgorodispersible tablet$0.31$9.22
donepezil hcl 5 mg tablet5 mgtablet$0.043$1.29
donepezil hcl 23 mg tablet23 mgtablet$0.77$23.14
Same medicine, other countries

Donepezil 10 mg tablet: the United States vs 4 other countries

United Kingdom$0.046
United States (this page)$0.049
United Arab Emirates$0.094
Australia$0.10
South Africa$0.47
Lowest listed price per tablet (USD)
By country
CountryPrice typePer tablet (local)Per unit (USD)
United KingdomNHS Drug Tariff price£0.034$0.046
United Arab EmiratesAbu Dhabi DoH public priceAED 0.35$0.094
AustraliaPBS approved ex-manufacturer priceA$0.15$0.10
South AfricaSingle Exit Price (SEP)R7.86$0.47

Countries publish different kinds of price (manufacturer, reimbursement or retail), so differences are partly due to what is measured. Converted at official US dollar pegs (AED, SAR) and ECB reference rates of 23 October 2026.

What this price means

How NADAC prices work in the United States

Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.

Read the full guide to medicine prices in the United States.

Strengths and forms

Every strength and form of donepezil in the United States

Strengths and forms
Strength and formProductsCheapest packCheapest per unit
10 mg tablet1$0.049$0.049
5 mg orodispersible tablet1$0.28$0.28
10 mg orodispersible tablet1$0.31$0.31
5 mg tablet1$0.043$0.043
23 mg tablet1$0.77$0.77

Different strengths and forms (for example slow-release or dissolving tablets) are not interchangeable without your doctor's advice.

A–Z

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Quick answers

Frequently asked questions

How much does donepezil cost in the United States?
Official NADAC prices for donepezil in the United States range from $0.049 to $0.77 per pack across 5 listed products. The cheapest 10 mg tablet works out at $0.049 each (about $0.049).
What kind of price is this?
It is the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
What is the cheapest donepezil 10 mg tablet in the United States?
Generic at $0.049 for 1 tablet, or $0.049 per tablet.
How much does donepezil cost without insurance?
US pharmacies pay about $0.049 per tablet for 10 mg tablet, or $1.47 for 30 (NADAC, Oct 2026). Without insurance you pay that cost plus the pharmacy's dispensing fee and margin, so cash prices are higher and vary a lot between pharmacies. Asking for the generic, comparing pharmacies and using a discount program usually brings the price closest to this cost.
Is NADAC the retail price of donepezil?
No. NADAC is what pharmacies pay to buy the drug. It is the closest public benchmark for the real cost of a generic, which is why Medicaid uses it to pay pharmacies, but the price at the counter includes fees on top.
Is donepezil cheaper in other countries?
For 10 mg tablet, the lowest listed price per tablet is $0.046 in the United Kingdom, $0.094 in the UAE, $0.10 in Australia and $0.47 in South Africa, compared with $0.049 in the United States. Each country publishes a different type of price, so treat this as a rough guide.
Evidence

Sources

  1. Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error