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Medicine prices in South Africa

Darunavir and Ritonavir Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending3 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP) per tablet
R12.45

Cheapest 400 mg / 50 mg tablet: RONIVID 400/50 mg, R747 for 60 tablets. Official SEP list, Oct 2026.

≈ $0.75 per tablet
R747
cheapest pack (60 tablets)
R374
30 tablets (1 a day for a month)
3
listed products
SEP
price type
What you actually pay

What a patient pays for darunavir and ritonavir in South Africa

R747
official SEP for RONIVID 400/50 mg, 60 tablets
+ R258
maximum dispensing fee incl. VAT
Up to R1,006
you pay at the pharmacy

Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.

3 products

3 different brand names across 1 strength are on the official list.

Interactive

How much will Darunavir and Ritonavir 400 mg / 50 mg tablet cost you?

tablets per day: 1 a day
Supply
30 days90 days1 year

Your doctor decides how many tablets you need. This is a cost estimate only, using R12.45 per tablet.

Estimated cost
R374
For a full yearR4,545
Per tablet in USD$0.750
Every listed product

All 3 darunavir and ritonavir products in South Africa

Darunavir and Ritonavir official prices in South Africa
ProductStrength and formPackPricePer unit
RONIVID 400/50 mg400 mg / 50 mg film-coated tablet60 tabletsR747R12.45
Darunavir Ritonavir 450mg Mylan400 mg / 50 mg film-coated tablet60 tabletsR768R12.79
Zadurna original400 mg / 50 mg film-coated tablet60 tabletsR768R12.79
RONIVID 400/50 mgR12.45
Darunavir Ritonavir 450mg MylanR12.79
ZadurnaR12.79
Darunavir and Ritonavir 400 mg / 50 mg tablet: price per tablet by product (ZAR)
What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

Read the full guide to medicine prices in South Africa.

Its ingredients on their own
Brand names

Brands of darunavir and ritonavir in South Africa

2 brand names of darunavir and ritonavir are on the official list in South Africa. Each brand page shows every pack and the cheapest alternative with the same strength.

Who supplies it

Darunavir and Ritonavir manufacturers in South Africa

The official list names 2 manufacturers for darunavir and ritonavir in South Africa: Hetero Drugs South Africa (Pty) Ltd and Viatris Healthcare (Pty) Ltd.

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Quick answers

Frequently asked questions

How much does darunavir and ritonavir cost in South Africa?
Official SEPs for darunavir and ritonavir in South Africa range from R747 to R768 per pack across 3 listed products. The cheapest 400 mg / 50 mg tablet works out at R12.45 each (about $0.75).
What kind of price is this?
It is the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.
How much will I pay for darunavir and ritonavir at a pharmacy in South Africa?
Up to R1,006 for RONIVID 400/50 mg (60 tablets). Single Exit Price plus the maximum pharmacist dispensing fee and VAT on the fee. Medical schemes may pay part.
What is the cheapest darunavir and ritonavir 400 mg / 50 mg tablet in South Africa?
RONIVID 400/50 mg at R747 for 60 tablets, or R12.45 per tablet. 2 other products have the same strength.
What brands of darunavir and ritonavir are sold in South Africa?
2 brand names are on the official list, including Ronivid (from R747) and Zadurna (from R768).
Who makes darunavir and ritonavir sold in South Africa?
Manufacturers named on the official list include Hetero Drugs South Africa (Pty) Ltd and Viatris Healthcare (Pty) Ltd.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. National Department of Health, South Africa. Dispensing fee for pharmacists (Notice 5364, Government Gazette 51352, 4 October 2024): maximum fee by SEP band, excluding VAT. archive.gazettes.africa/archive/za/2024/za-government-gazette-dated-20. Retrieved 25 October 2026.
  3. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error