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Medicine prices in the United States

Daptomycin Price in the United States (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 31 October 2026How we get our data
Lowest NADAC pharmacy acquisition cost
$25.56

Average pharmacy cost for generic daptomycin 500 mg injection. CMS NADAC file, Oct 2026.

≈ $25.56
$25.56
lowest per unit
1
strengths
1
strength and form
NADAC
price type (CMS)
Cash price

Daptomycin cost without insurance

The figures here are what US retail pharmacies pay for generic daptomycin. If you pay cash, the pharmacy adds a dispensing fee and its margin, so expect to pay more than this, and prices differ between pharmacies for the same prescription.

With insurance or Medicare Part D you usually pay a fixed co-pay or co-insurance instead. Ask for the generic rather than the brand, compare a few pharmacies, and check discount programs: for cheap generics a cash price can be lower than your co-pay.

Every listed product

All 1 daptomycin product in the United States

Daptomycin official prices in the United States
Generic (NADAC description)StrengthFormPer unit30 units
daptomycin 500 mg vial500 mginjection$25.56$767
What this price means

How NADAC prices work in the United States

Prices on this page are the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.

Read the full guide to medicine prices in the United States.

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Quick answers

Frequently asked questions

How much does daptomycin cost in the United States?
Official NADAC prices for daptomycin in the United States range from $25.56 to $25.56 per pack across 1 listed product.
What kind of price is this?
It is the National Average Drug Acquisition Cost (NADAC): the average price US retail pharmacies pay wholesalers for the drug, per tablet, capsule, mL or gram, from a monthly survey run for the Centers for Medicare & Medicaid Services (CMS). It is not the price on your receipt. Pharmacies add a dispensing fee and a margin, so the cash price without insurance is higher, often much higher, while your co-pay with insurance depends on your plan. Discount programs and low-cost pharmacies often sell common generics close to this cost plus a fee.
How much does daptomycin cost without insurance?
US pharmacies pay about $25.56 per unit (NADAC, Oct 2026). Without insurance you pay that cost plus the pharmacy's dispensing fee and margin, so cash prices are higher and vary a lot between pharmacies. Asking for the generic, comparing pharmacies and using a discount program usually brings the price closest to this cost.
Is NADAC the retail price of daptomycin?
No. NADAC is what pharmacies pay to buy the drug. It is the closest public benchmark for the real cost of a generic, which is why Medicaid uses it to pay pharmacies, but the price at the counter includes fees on top.
Evidence

Sources

  1. Centers for Medicare & Medicaid Services (CMS). NADAC (National Average Drug Acquisition Cost) 2026, weekly file as of 28 October 2026 (generic prescription drugs). data.medicaid.gov/dataset/fbb83258-11c7-47f5-8b18-5f8e79f7e704. Retrieved 31 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error