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Brand prices in South Africa

Sylvant Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R10,050

Sylvant (siltuximab): 100 mg injection, 1. Official SEP list, Oct 2026.

≈ $606
R10,050 – R40,200
per pack
2
strengths
2
listed packs
SEP
price type
2 countries

list Sylvant: South Africa and United Arab Emirates.

Every listed pack

Sylvant strengths, packs and prices in South Africa

Sylvant official prices in South Africa
ProductStrength and formPackPricePer unit
SYLVANT original100 mg injection1R10,050—
SYLVANT original400 mg injection1R40,200—

Sylvant is sold in South Africa as 100 mg injection and 400 mg injection. The official list names Key Oncologics (Pty) Ltd as the manufacturer. It is a Schedule 4 medicine. The South African price database marks it as the originator (first) brand.

Same brand, other countries

Sylvant price in other countries

By country
CountryPacksCheapest pack (local)In USDPrice type
South Africa (this page)2R10,050$606Single Exit Price (SEP)
United Arab Emirates2AED 3,089$841Abu Dhabi DoH public price

Pack sizes differ between countries, and each country publishes a different kind of price.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every siltuximab product and price in South Africa, or read the guide to medicine prices in South Africa.

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Quick answers

Frequently asked questions

How much does Sylvant cost in South Africa?
Sylvant costs from R10,050 to R40,200 depending on strength and pack. This is the Single Exit Price.
What is the generic name of Sylvant?
Sylvant contains siltuximab. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.
Who makes Sylvant?
The official list names Key Oncologics (Pty) Ltd as the manufacturer of Sylvant products sold in South Africa.
What schedule is Sylvant in South Africa?
Sylvant is a Schedule 4 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error