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Brand prices in South Africa

Prolia Price in South Africa (2026)

Compiled by the TrustClinix data team · Medical review pending2 official sourcesPrices last checked 25 October 2026How we get our data
Lowest Single Exit Price (SEP)
R3,831

Prolia (denosumab): 60 mg/ml pre-filled syringe, 1. Official SEP list, Oct 2026.

≈ $231
R3,831
per pack
1
strength
1
listed pack
SEP
price type
3 countries

list Prolia: South Africa, Saudi Arabia and United Arab Emirates.

Every listed pack

Prolia strengths, packs and prices in South Africa

Prolia official prices in South Africa
ProductStrength and formPackPricePer unit
Prolia 60 mg original60 mg/ml pre-filled syringe1R3,831—

Prolia is sold in South Africa as 60 mg injection. The official list names Amgen South Africa (Pty) Ltd as the manufacturer. It is a Schedule 4 medicine. The South African price database marks it as the originator (first) brand.

Same brand, other countries

Prolia price in other countries

By country
CountryPacksCheapest pack (local)In USDPrice type
South Africa (this page)1R3,831$231Single Exit Price (SEP)
Saudi Arabia1SAR 779$208SFDA public price
United Arab Emirates1AED 1,181$321Abu Dhabi DoH public price

Pack sizes differ between countries, and each country publishes a different kind of price.

What this price means

How SEPs work in South Africa

Prices on this page are the Single Exit Price: the one legal price at which the manufacturer may sell the pack in South Africa, including VAT and a logistics fee. Pharmacies and dispensing doctors add a regulated dispensing fee plus VAT on top. For cheap medicines this fee is a large share of what you pay, and can be more than the medicine itself, so the counter price can be much higher than the SEP. Medical schemes may pay all or part of it.

See every denosumab product and price in South Africa, or read the guide to medicine prices in South Africa.

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Quick answers

Frequently asked questions

How much does Prolia cost in South Africa?
Prolia costs R3,831. This is the Single Exit Price.
What is the generic name of Prolia?
Prolia contains denosumab. Medicines with the same active ingredient, strength and form work the same way, though inactive ingredients can differ.
Who makes Prolia?
The official list names Amgen South Africa (Pty) Ltd as the manufacturer of Prolia products sold in South Africa.
What schedule is Prolia in South Africa?
Prolia is a Schedule 4 medicine in South Africa. Schedule 0–1 medicines can be sold without a prescription; Schedule 3 and above need one.
Evidence

Sources

  1. National Department of Health, South Africa. Database of Medicine Prices (Single Exit Price), effective 1 October 2026. www.health.gov.za/nhi-pee/. Retrieved 25 October 2026.
  2. European Central Bank. Euro foreign exchange reference rates (2026-10-23). www.ecb.europa.eu/stats/eurofxref/eurofxref-daily.xml. Retrieved 25 October 2026.

Important: These are published reference prices and estimates, not a quote, and not medical advice. Actual costs depend on the hospital, your health, the exact treatment and your insurance. Always confirm the price with the provider before treatment. Read our disclaimer · Report an error